Interested in participating in our research? We are currently enrolling ages 2 to 99. Learn more at unhideNow.org
Uncovering The Overlap
We are uniting patients, researchers, and clinicians to advocate for and research over 30+ neuroinflammation-linked conditions with overlapping causes, symptoms, comorbidities, and treatment responses.
Brain inflammation, or neuroinflammation, occurs when the immune system’s inflammatory response impacts the brain, nervous system, or spinal cord.
Inflammation, or the inflammatory process, is part of your immune system’s normal reaction to an illness, infection, or injury. It can be caused by viruses, infections, injuries, even allergies. Inflammation typically resolves when the infection clears, the injury heals, or when you avoid contact with the allergen.
For some people, this process triggers an endless loop of neuroinflammation and debilitating symptoms like:
- Extreme fatigue
- Brain fog
- Severe sleep issues
- Dramatic mood or behavior changes
- Depression
- Anxiety
- Panic attacks
- and more.
“Inflammation in your brain can strike at the very core of who you are— impacting how you think, feel, move, and act.”
— Christy Jagdfeld, Brain Inflammation Collaborative Co-founder, President & CEO, Caregiver, & Advocate
The connections between these symptoms, brain inflammation, and the immune system are poorly understood.
The Brain Inflammation Collaborative works with patients, researchers, and clinicians to better understand these devastating conditions and improve health outcomes for everyone impacted by neuroinflammation.
Patients & Caregivers
Find out about the triggers & symptoms of brain inflammation, associated conditions, and how you can help fuel better diagnosis and treatment for all.
Researchers & Clinicians
Drive scientific advancement through patient-centered, longitudinal, real-world clinical research, informing better standards of care for neuroinflammation.
Advocates & Supporters
Uncover a better path forward for people impacted by neuroinflammation, who have been misunderstood, misdiagnosed, and dismissed for too long.
Why Now?
Up to 60% of people with mental health symptoms like depression, anxiety, OCD, panic attacks, and behavioral issues do not respond to traditional treatment methods.
For many with treatment-resistant symptoms, the underlying cause may be neuroinflammation associated with immune system dysfunction or long-term health issues after a virus or bacterial infection, allergies, or an injury.
These conditions have historically been studied, diagnosed, and treated separately. But now, a growing body of evidence is uncovering the truth. They may have more in common than we thought, and those similarities could hold the key to better health for all people impacted by brain inflammation.
Few real-world, longitudinal studies have analyzed the intersections between risks, symptoms, and the progression of infection-associated chronic conditions and autoimmune illnesses.
Our research priorities are fueled by this critical research gap.
The Brain Inflammation Collaborative (BIC), in partnership with Solve M.E., is excited to announce the launch of unhide®, a digital health tool designed to uncover hidden connections between inflammation, chronic illness, and overall health. unhide® is an exciting resource for patients and researchers alike. The easy-to-use, secure platform allows patients to contribute data through symptom surveys, validated assessments, wearable devices, and health history to support research across 30+ related conditions.
