Newsletters

Stay up to date with our journey, stories, and impact—one email newsletter at a time.

Looking for a past Mental Matters newsletter edition? You’re in the right place.

Here you’ll find all our previous newsletters, filled with community updates, inspiring stories, upcoming events, and ways to get involved.

Whether you’re catching up or revisiting a favorite story, we’re glad you’re here.

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2025

Issue 49, Published 1-6-26

Thank you to our supporters, 2025 partnerships, unhide® platform launch, and 3,000+ participant data contributions.
Our in-house patient-centered studies, including those on IVIG in PANS, brain fog, mood and behavior, and the microbiome in ME/CFS and Long COVID.

Issue 47, Published 12-12-25

Catch the latest webinar recording
Discover our exciting progress and preliminary findings from patient-centered research this year.
Dr. Megan Fitzgerald answers more audience questions on tracking symptoms, imaging neuroinflammation, and unmasking hidden pathogens.
Explore new articles on the unhide® Brain Fog Study, oxidative stress in Long COVID/ME/CFS, a parent’s story, and how you can drive research forward.

Issue 45, Published 10-17-25

New research uncovers elevated AMPA receptors as a potential direct driver of brain fog in Long COVID—explore the findings and what they could mean for treatment.
Exclusive interview with MCAS expert Dr. Lawrence Afrin who reveals surprising insights into mast cells, their role in chronic conditions, and overlaps with POTS, EDS, and more.
Latest breakthroughs include a promising blood test for ME/CFS, AI-accelerated antibiotic for Crohn’s, a new gene linked to hypermobile EDS, and remyelination compounds for MS

Issue 43, Published 09-18-25

Key findings uncover gut dysbiosis clues, mitochondrial-peroxisomal vicious cycle, and promising clinical trial candidates like metformin and rapamycin.
Childhood inflammation that peaks early in life is linked to higher adult risks of psychosis, depression, and insulin resistance.
A quick health hack video for better vitality.

Issue 41, Published 08-22-25

Explore the Hi-OxSR rebreather’s potential to improve brain blood flow and oxygen delivery for Long COVID brain fog.
Dr. Megan Fitzgerald joins the Scientific Committee for the 3rd Long COVID International Conference—learn about submission opportunities and key topics.
Breakthrough launch: unhide® Solve Together Unified Platform partners with Solve M.E. to accelerate research across inflammation-related chronic conditions.

Issue 39, Published 08-13-25

Groundbreaking AI from Stanford could slash years of autoimmune misdiagnosis, watch the video to learn how it analyzes immune receptors with 99% accuracy.
CEO Christy Jagdfeld shares her personal journey navigating her daughter’s infections, neuroinflammation, OCD, and the challenges of finding answers.
New partnership with Solve M.E. launches the unhide® Solve Together Unified Platform.

Issue 37, Published 07-18-25

New partnership with Long Covid Families announced, explore how we’re teaming up to advance pediatric Long COVID research, advocacy, and family support.
Pediatric Long Covid Awareness Week July 21-25, join events, including a July 22 webinar on mental health impacts featuring Dr. Megan Fitzgerald.

Issue 35, Published 06-21-25

Exciting roadmap ahead: Brain Storm newsletter launches summer 2025, Unified Platform opens for adults, then pediatrics, plus new brain fog study collaboration.
Meet Natasha, Director of Marketing—discover her inspiring background in public health, advocacy for chronic illness, and passion for accessibility.
Emerging insights on HPA axis dysfunction in ME/CFS/Long COVID, CO2’s potential role in brain function and symptoms, plus promising Rituximab findings for immune-triggered OCD in youth.

Issue 33, Published 05-12-25

The role of brain-derived neurotrophic factor in human health and disease.
The Brain Inflammation Collaborative partners with Solve ME, Chronical Bio, Complex Disorders Alliance, and Care Evolution to accelerate research on ME/CFS, Long COVID, and other IACCs.

Issue 31, Published 04-16-25

Two new Brain Inflammation Collaborative researchers joined our growing team.
Our most popular content is shared with you.

Issue 29, Published 03-05-25

Publication Spotlight: Pediatric Acute-Onset Neuropsychiatric Syndrome
The Little Things: Can hydrogen-rich water reverse brain aging?

Issue 27, Published 02-11-25

How inhibiting the inflammasome in your brain’s white blood cells is a promising new Alzheimer’s therapeutic target.
What do you want more of? A quick newsletter survey.
The science behind multivitamins and why a methylated multivitamin might be the better health-boosting option.

Issue 25, Published 01-28-25

A new study finds how wildfire smoke might trigger neuroinflammation.
Last week on the world wide web, featured social media content.
A do-it-yourself way to quickly clean your home air during high smoke conditions.

Issue 23, Published 01-06-25

A new study reveals how peripheral inflammation targets the brain.
Last week on the world wide web, featured social media content.
Can compression garments reduce the symptoms of POTS?

Issue 50, Published 1-15-26

Long COVID microclots wrapped in DNA webs make them difficult to break. Could this partly explain your symptoms of fatigue and brain fog in Long COVID?
Misfolded fibrin in microclots forms tough, amyloid-like structures seen in ME/CFS, Alzheimer’s, Parkinson’s, and more.
Brain storm briefs covering the latest discoveries related to Long COVID, PANS, autoimmunity, neuroinflammation, and more.

Issue 48, Published 12-18-25

The NLRP3 inflammasome drives inflammation in many chronic diseases like Alzheimer’s and Lupus, learn how it works and why it’s overactivated.
A robust pipeline of NLRP3 inhibitors is advancing, discover the candidates, trials, and when approvals might happen.
Exciting new studies on treatments for depression, ME/CFS, and more.

Issue 46, Published 11-13-25

Free radicals damage cells in relentless chain reactions—learn their sources, consequences, and evidence-backed antioxidant strategies to fight back.
Free radicals damage cells in relentless chain reactions—learn their sources, consequences, and evidence-backed antioxidant strategies to fight back.

Issue 44, Published 10-14-25

The unhide® Solve Together Unified Platform now enrolls children and teens aged 2-17.
Pediatric enrollment opens new doors to understanding chronic illnesses’ impact on brain development—learn how families can join at unhidenow.org.
Join a free webinar on how the Unified Platform advances research across ME/CFS, Long COVID, and neuroinflammatory conditions.

Issue 42, Published 08-28-25

We are partnering with Solving MS
Collaboration aims to expand comparative research, innovate with AI-driven drug discovery, empower patient voices, and provide accessible education across MS and related conditions.
Learn about Solving MS’s unique patient-powered database and how together we’re accelerating treatments for brain inflammation, Long COVID, and more.

Issue 40, Published 08-14-25

Brain Inflammation Collaborative partners with Solve M.E. to launch the unhide® Solve Together Unified Platform.
Empower yourself by logging health data, connecting wearables, generating doctor reports, and getting pacing alerts.
Learn why joining accelerates better diagnostics and treatments for neuroinflammatory illnesses.

Issue 38, Published 08-01-25

Free educational webinar coming August 7th.
Meet new team member Anvita, our newest Clinical Research Associate with expertise in cognitive neurosciences and passion for accessible neuropsychiatric care.

Issue 36, Published 03-13-25

New study uncovers a genetic variant that, combined with mono, may explain why some EBV-infected people develop MS.
High ANA titers and NETosis could be overlooked drivers of autoimmunity in conditions like Lupus, Sjögren’s, Long COVID, and MS, explore the science behind these hidden clues.
Dr. Teri Sanor shares her family’s journey uncovering chronic Lyme and infections as causes of neurological symptoms, discover why they’re often misdiagnosed.

Issue 34, Published 06-05-25

Last chance to participate in the survey on IVIG treatment for PANDAS/PANS until June 11th, 2025; open to patients and caregivers.
Launching “The Brain Storm,” a monthly research-focused newsletter this summer, and a new study on brain fog in collaboration with Columbia University starting fall 2025.
COVID-19’s reversible impact on IQ/brain fog, a genetic link between endometriosis and immune disorders

Issue 32, Published 04-29-25

Check out our new website.
Our mission is to uncover better ways to diagnose and treat neuroinflammation and its associated mood, behavior, and mental health symptoms by partnering with advocacy groups, clinicians, researchers, and individuals to conduct research, raise awareness, and unite efforts toward timely, compassionate care for affected families.

Issue 30, Published 03-13-25

IACCs – A Guide by the Long Covid Initiative
Interested in learning about the research currently underway?

Issue 28, Published 02-26-25

The economic impacts of IVIg Therapy to treat PANS
What is IVIg Therapy?
How IVIg might be able to help people with Long Covid, PANS/PANDAS, POTS, ME/CFS, and more.

Issue 26, Published 02-04-25

A new study finds that regulatory T cells safeguard against neuroinflammation and memory loss.
Last week on the world wide web, featured social media content.

Issue 24, Published 01-14-25

A review of our collaborative efforts with the Stanford Immune Behavioral Health Clinic in 2024.
Last week on the world wide web, featured social media content.
The science behind how wearable devices measure stress.

2024

Issue 21, Published 12-23-24

This week on the World Wide Web, featured social media content.

Issue 19, Published 12-03-24

Learn why the Brain Inflammation Collaborative is uniquely positioned to help researchers solve complex neuroimmune axis and mental health conditions.

Issue 17, Published 11-18-24

A new antibody-based nasal spray used to treat Alzheimer’s disease.
Dopamine receptor autoantibodies found in the serum of children with PANDAS/PANS.
The correct way to stop a cold using vitamin C ahead of cold and flu season.

Issue 15, Published 11-04-24

The science that might explain why vagus nerve stimulation reduces POTS symptom severity
How to stimulate your vagus nerve to possible improve symptoms of ME/CFS, Long COVID, POTS, and more.

Issue 13, Published 10-14-24

Why including long COVID patients as active collaborators is key to future long COVID clinical trial success.
New insights into how near-infrared light might reduce chronic inflammation.
A fresh perspective reveals why going outdoors is good for your health.

Issue 11, Published 09-23-24

Join us and hundreds of researchers, clinicians, advocates, patients, and caregivers- United for IACCI Research
Inflammatory microplastics are found in the brain.
Autoimmune and allergic illnesses are on the rise-
but why?

Issue 09, Published 09-10-24

Can anxiety, mental fog, or trouble sleeping be caused by brain inflammation?
Quote from our PI, Dr. Megan Fitzgerald about the hidden clues brain inflammation might be present.
The Brain Inflammation Collaborative’s goal.

Issue 07, Published 08-26-24

New discoveries in the genetic causes of some autoimmune conditions
A potential connection between seasonal allergies and depression
How to manage stress through the nervous system

Issue 05, Published 08-05-24

Separating fact from fiction
A note from our PI, Dr. Megan Fitzgerald
A refreshing anti-inflammatory drink recipe you must try.

Issue 03, Published 07-22-24

Introducing Principal Investigator Dr. Megan Fitzgerald!
Dr. Denise Calaprice-Whitty transitions to Senior Program Advisor
Food for Thought

Issue 01, Published 06-30-24

Fast Facts – Treatment-Resistant Depression
Welcome to our new interns, Chris, Noah, and Ryan!

Issue 22, Published 12-30-24

Reflecting on progress made in 2024
Exciting new studies being launched in 2025
New partnership announcements on the horizon.

Issue 20, Published 12-09-24

Year end review of our progress and what is to come.
Interview with Claimable Co-founder and CEO Warris Bokhari
Navigating health insurance claims and denials

Issue 18, Published 11-25-24

Happy Thanksgiving from our CEO, Christy Jagdfeld
How the harmful pesticide glyphosate can harm your gut health and what to prevent it.

Issue 16, Published 11-11-24

A new biological driver of mental health, how a liver receptor might control our mental health.
A newly-invented devise measures the amount of neuroinflammatory microplastics in the liquids we drink.

Issue 14, Published 10-21-24

What sets the Brain Inflammation Collaborative apart from other neuroinflammation-centered non-profits
How you can help drive meaningful advancements to treat neuroimmune axis conditions and mental health.

Issue 12, Published 10-07-24

The Brain Inflammation Collaborative’s preliminary IVIg study results.
California passes legislation protecting families impacted by PANS seeking IVIg treatment.
The connection between alcohol use and anxiety

Issue 10, Published 09-16-24

Breaking the cycle of unimpactful, inconsistent clinical trials addressing Long Covid
New connection between COVID-19 and blood clotting
Is the brain prone to inflammation?